CP-39,332

CP-39,332
Clinical data
Other names	CP-39332; CP39332
Routes of; administration	Oral
Drug class	Serotonin–norepinephrine reuptake inhibitor (SNRI)
ATC code	None;
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name 1,2,3,4-tetrahydro-N-methyl-4-phenyl-2-naphthalenamine;
CAS Number	61764-60-1 ;
PubChem CID	15657209;
DrugBank	DB09193;
ChemSpider	23189744;
UNII	R0YEK8P3H4;
ChEMBL	ChEMBL104444;
CompTox Dashboard (EPA)	DTXSID20576434 ;
Chemical and physical data
Formula	C17H19N
Molar mass	237.346 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CNC1CC(C2=CC=CC=C2C1)C3=CC=CC=C3;
	InChI InChI=1S/C17H19N/c1-18-15-11-14-9-5-6-10-16(14)17(12-15)13-7-3-2-4-8-13/h2-10,15,17-18H,11-12H2,1H3; Key:HLOCJJORRHQDKS-UHFFFAOYSA-N;

CP-39,332 is a serotonin–norepinephrine reuptake inhibitor (SNRI) of the 2-aminotetralin family.^[1] Tametraline (1R,4S-), CP-24,442 (1S,4R-), CP-22,185 (cis-), and CP-22,186 (trans-) are stereoisomers of the compound and show varying effects on monoamine reuptake.^[1] None of them were ever marketed.

References

1 2 Koe BK (December 1976). "Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain". The Journal of Pharmacology and Experimental Therapeutics. 199 (3): 649–61. doi:10.1016/S0022-3565(25)30726-3. PMID 994022.

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