N,N-Dimethyl-2-aminoindane

N,N-Dimethyl-2-aminoindane
Clinical data
Drug class	dopaminergic agent; cholinergic agent
ATC code	none;
Identifiers
	IUPAC name N,N-Dimethyl-2,3-dihydro-1H-inden-2-amine;
CAS Number	51864-45-0;
PubChem CID	3016704;
ChemSpider	2284609;
ChEMBL	ChEMBL1193475;
CompTox Dashboard (EPA)	DTXSID40199826;
Chemical and physical data
Formula	C11H15N
Molar mass	161.248 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES JHJKWSLLPQWCDF-UHFFFAOYSA-N;
	InChI InChI=1S/C11H15N/c1-12(2)11-7-9-5-3-4-6-10(9)8-11/h3-6,11H,7-8H2,1-2H3; Key:JHJKWSLLPQWCDF-UHFFFAOYSA-N;

N,N-Dimethyl-2-aminoindane (NNDMAI) is a dopaminergic agent and a cholinergic agent.^[1]^[2]

Pharmacology

NNDMAI exerts a nicotinic-like cholinergic effect, causing contractions of the ileum in in vitro testing of guinea pig samples.^[2]

↑ Cannon JG, Perez JA, Pease JP, Long JP, Flynn JR, Rusterholz DB, et al. (July 1980). "Comparison of biological effects of N-alkylated congeners of beta-phenethylamine derived from 2-aminotetralin, 2-aminoindan, and 6-aminobenzocycloheptene". Journal of Medicinal Chemistry. 23 (7): 745–749. doi:10.1021/jm00181a009. PMID 7190613.
1 2 Little HJ, Rees JM (November 1980). "In vitro actions of NN-dimethyl-2-aminoindane and related compounds". The Journal of Pharmacy and Pharmacology. 32 (11): 751–756. doi:10.1111/j.2042-7158.1980.tb13060.x. PMID 6110722.