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This is the new home of the Subcellular Drug Transport Laboratory at the Department of Pharmaceutical Sciences at the Universityof Michigan College of Pharmacy. As of December 22, 2007, we have become an Open Notebook Science laboratory. This means that all our laboratory notebooks will be blogs. C& EN News recently featured an informative, relevant article about Open Science. Here is how an Open Notebook Science Lab works: Only the blog organizer (the lab PI, Gus Rosania) can delete pages or remove uploaded files. Members can make changes to the pages, upload files, add new pages and otherwise edit content (unless a page is locked). Non-members can view all pages and make comments using the discussion tab at the top of the page. Any edits or changes made by members are stored, and they can be reviewed using the history tab at the top of each page. Non-members cannot alter the content of the pages. Pages should be locked, if you want to prevent the page from being edited or modified by another member, without the permission of the blog organizer (Gus Rosania). Open Notebook Science was born from the UsefulChem wikispace developed by Jean-Claude Bradley at Drexel University (Thank You, Jean-Claude!). Open Notebook Science is ideally suited for community-wide collaborative research projects involving mathematical modeling and computer simulation work, as it allows researchers to document model development in a step-by-step fashion, then link model prediction to experiments that test the model, and in turn, use feeback from experiments to evolve the model. By making our laboratory notebooks public, the evolutionary process of a model can be followed in its totality by the interested reader. Researchers from laboratories around the world can now follow the progress of our research day-to-day, borrow models at various stages of development, comment or advice on model developments, discuss experiments, ask questions, provide feedback, or otherwise contribute to the progress of science in any manner possible. Because of the nature of the blogs, any results from our laboratory notebooks should be considered tentative or preliminary. Researchers interested in borrowing models, results, experiments, or other insights posted in our notebooks are able to do so at their own risk. We only ask that our work is used and credited appropriately, as detailed in the creative commons license. To facilitate the maintainance and sharing of our research results, we are in the process of porting our cellular pharmacokinetic (1CellPK) models into Virtual Cell. An article about the successful porting of the 1CellPK models is being prepared, to be published in mid-late 2008. We have also joined The Synaptic Leap, which is an Open Source collaborative drug discovery project aimed at facilitating development of treatments for neglected disease that are mostly prevalent in impoverished nations of the world. Rosania Research Group Wikispace Members and Collaborators Rosania Research Group Project Blogs Rosania Research Group Laboratory Notebooks Rosania Research Group in Second Life Rosania Research Group 1CellPK Published Models Rosania Research Group 1CellPK Published Simulation Results Rosania Research Group Published CAIAs and Visualizations Rosania Research Group Published Image Datasets Lab Introduction Poster for Recruit on 02.22.2008  080225 R lab overall for recruit.pdf
Note that the content you create on http://1cellpk.wikispaces.com is licensed under the Creative Commons Attribution Share-Alike 3.0 License. Please only submit content that you write yourself or that is in the public domain. Learn more about our open content policy. |
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