Tag: Eukaryotic genome annotation

Now Available: RefSeq Release 237

Now Available: RefSeq Release 237

RefSeq release 237 is now available online and from the FTP site! You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings.    

What’s included in this release?  

As of August 31, 2026, this full release incorporates genomic, transcript, and protein data containing:

  • 645,505,406 records 
  • 495,290,394 proteins 
  • 86,067,871 RNAs 
  • Sequences from 184,752 organisms 

Continue reading “Now Available: RefSeq Release 237” →

Now Available: RefSeq Release 236

Now Available: RefSeq Release 236

RefSeq release 236 is now available online and from the FTP site! You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings.    

What’s included in this release?  

As of July 6, 2026, this full release incorporates genomic, transcript, and protein data containing:   

  • 629,953,391 records  
  • 482,864,455 proteins  
  • 83,806,434 RNAs  
  • Sequences from 182,465 organisms  

Continue reading “Now Available: RefSeq Release 236” →

New Minimum Requirements for Prokaryotic and Eukaryotic Genome Submissions

New Minimum Requirements for Prokaryotic and Eukaryotic Genome Submissions

High-quality submissions make genome data more valuable for the entire research community. To support data quality and usability, the International Nucleotide Sequence Database Collaboration (INSDC) has established minimum criteria for genome submission acceptance. Genome submissions to GenBank must meet the applicable INSDC minimum requirements to be processed, assigned accession numbers, and released publicly. These changes are part of NCBI’s broader effort to implement INSDC minimum specifications across sequence data resources and submission workflows. 

What’s new? 

Starting January 2027, the following new requirements will be validated at the time of submission in Submission Portal-Genome:  Continue reading “New Minimum Requirements for Prokaryotic and Eukaryotic Genome Submissions” →

RefSeq Release 228 is Available!

RefSeq Release 228 is Available!

Check out RefSeq release 228, now available online and from the FTP site. You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings.

What’s included in this release?

As of January 3, 2025, this full release incorporates genomic, transcript, and protein data containing:

  • 513,096,240 records, including
  • 391,903,900 proteins
  • 67,997,702 RNAs
  • Sequences from 162,138 organisms 

Continue reading “RefSeq Release 228 is Available!” →

New RefSeq Annotations Now Available!

New RefSeq Annotations Now Available!

In February and March, the NCBI Eukaryotic Genome Annotation Pipeline released forty-six new annotations in RefSeq!

New Annotations
  • Aedes albopictus (Asian tiger mosquito)
  • Anolis carolinensis (green anole)
  • Armigeres subalbatus (mosquito)
  • Bacillus rossius redtenbacheri (walking stick)
  • Bolinopsis microptera (comb jelly)
  • Bombyx mori (domestic silkworm)
  • Bubalus kerabau (carabao)
  • Candoia aspera (snake)
  • Cavia porcellus (domestic guinea pig) 
  • Continue reading “New RefSeq Annotations Now Available!” →
Now Available: RefSeq Release 223

Now Available: RefSeq Release 223

Check out RefSeq release 223, now available online and from the FTP site. You can access RefSeq data through NCBI Datasets.

What’s included in this release?

As of March 4, 2024, this full release incorporates genomic, transcript, and protein data containing:

  • 425,594,654 records
  • 316,329,937 proteins
  • 60,886,133 RNAs
  • sequences from 147,591 organisms 

Continue reading “Now Available: RefSeq Release 223” →

Gene Ontology (GO) Terms for NCBI RefSeq Eukaryotic Genomes

Gene Ontology (GO) Terms for NCBI RefSeq Eukaryotic Genomes

Are you interested in more functional information about protein-coding genes? We’ve expanded NCBI RefSeq’s Eukaryote Genome Annotation Pipeline (EGAP) to include Gene Ontology (GO) terms computed for most protein-coding genes. We are using the latest version of InterProScan, which now includes analysis based on PANTHER reference trees, on all NCBI RefSeq eukaryotic genomes. That means having comprehensive GO data with inferred biological process, molecular function, and cellular component terms matched with high-quality RefSeq annotations across hundreds of taxa to help drive your research. The data is available on individual records in NCBI’s Gene resource, NCBI Gene FTP, or in community standard .gaf formatted files with each RefSeq genome release on our FTP site.  Continue reading “Gene Ontology (GO) Terms for NCBI RefSeq Eukaryotic Genomes” →

RefSeq Release 221

RefSeq Release 221

RefSeq release 221 is now available online and from the FTP site. You can access RefSeq data through NCBI Datasets.

What’s included in this release?

As of November 6, 2023, this full release incorporates genomic, transcript, and protein data containing:

  • 404,657,610 records
  • 300,054,945 proteins
  • 57,882,313 RNAs
  • sequences from 143,819 organisms 

Continue reading “RefSeq Release 221” →

New Annotations in RefSeq!

New Annotations in RefSeq!

In July, August, and September, the NCBI Eukaryotic Genome Annotation Pipeline released fifty-six new annotations in RefSeq!

New Annotations
  • Achroia grisella (moth)
  • Acipenser ruthenus (sterlet)
  • Ahaetulla prasina (snake)
  • Alligator mississippiensis (American alligator)
  • Ammospiza caudacuta (bird)
  • Ammospiza nelsoni (bird)
  • Anopheles bellator (mosquito)
  • Anopheles coustani (mosquito)
  • Anopheles ziemanni (mosquito)
  • Arachis stenosperma (eudicot)
  • Carassius carassius (crucian carp)
  • Centropristis striata (black seabass)
  • Cornus florida (flowering dogwood) (pictured)
  • Corylus avellana (European hazelnut)
  • Corythoichthys intestinalis (scribbled pipefish) Continue reading “New Annotations in RefSeq!” →
RefSeq Release 220

RefSeq Release 220

RefSeq release 220 is now available online and from the FTP site. You can access RefSeq data through NCBI Datasets.

What’s included in this release?

As of September 5, 2023, this full release incorporates genomic, transcript, and protein data containing:

  • 391,350,361 records
  • 289,333,423 proteins
  • 56,423,426 RNAs
  • sequences from 141,099 organisms 

Continue reading “RefSeq Release 220” →