'Spider-Man: Brand New Day' trailer: Tom Holland yearns for Zendaya in action-packed first look

Perhaps we should change the title of Spider-Man: Brand New Day to Spider-Man: Mental Health Day, because goodness knows Peter Parker (Tom Holland) needs one.

At the end of Spider-Man: No Way Home, Doctor Strange (Benedict Cumberbatch) cast a spell that made everyone forget Peter's existence. The spell saved the multiverse, but it left Peter completely isolated, even from his girlfriend MJ (Zendaya) and his best friend Ned (Jacob Batalon).

Spider-Man: Brand New Day picks up four years after the end of Spider-Man: No Way Home, and it's clear that isolation has never gotten easier for Peter. In the trailer, he watches social media videos of MJ and Ned's first day at MIT and continues to yearn for their company — especially when they become his neighbors.

As if the crushing loneliness weren't enough, Spider-Man: Brand New Day also sees Peter going through some serious physical mutations including developing organic webs. For help on that matter, he goes to another expert on painful superhero transformations: Dr. Bruce Banner (Mark Ruffalo).

Bruce isn't the only MCU favorite to make an appearance in the trailer. Frank Castle/The Punisher (Jon Bernthal) is also in the mix, sassing Peter in a high-stakes car fight. Plus, villain Scorpion (Michael Mando) from Spider-Man: Homecoming is back, just one of many frightening bad guys Peter faces off with in the trailer.

Notably missing? Sadie Sink, who's confirmed to star in an as-yet undisclosed role. IGN speculates that she appears briefly in the trailer as a character in a long coat and grey hoodie, who seems to be a powerful psychic. Could this be our first look at the MCU's take on Jean Grey?

Will Peter find his way back into MJ and Ned's lives? What is happening to his powers? And how will Spider-Man: Brand New Day set up Avengers: Doomsday? We've got to wait until July to find out.

Spider-Man: Brand New Day hits theaters July 31.