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Query ChEMBL directly from a public S3 mirror with DuckDB. No download, no local database.

Python 10 2 Updated Oct 5, 2026

Search every structure in EMDB from Python — 60,895 cryo-EM maps by protein, organism, resolution, molecular weight and PDB cross-reference.

Python 2 Updated Oct 11, 2026

Unified high-performance Python client for object and file stores.

Python 87 28 Updated Oct 27, 2026

Clean-room Rust reimplementation of the STAR RNA-seq aligner, emulating STAR 2.7.11b (reproducible by design). Not the official STAR.

Rust 6 Updated Aug 5, 2026

Structured Outputs

Python 15,984 906 Updated Sep 21, 2026

GPU-native composable analytics engine

C++ 1,100 144 Updated Oct 27, 2026

Library to detect bots and jumble content

TypeScript 1 Updated Jun 25, 2025

Scalable Neuroglancer compatible Downsampling, Meshing, Skeletonizing, Contrast Normalization, Transfers and more.

Python 69 24 Updated Oct 26, 2026

DSPy: The framework for programming—not prompting—language models

Python 38,818 3,455 Updated Oct 27, 2026

High-level DICOM abstractions for the Python programming language

Python 241 62 Updated Oct 27, 2026

napari: a fast, interactive, multi-dimensional image viewer for python

Python 2,788 564 Updated Oct 27, 2026

Curate better data for LLMs

Python 1,070 106 Updated Mar 19, 2024

Interactive roadmaps, guides and other educational content to help developers grow in their careers.

TypeScript 370,547 45,156 Updated Oct 27, 2026

Kafka 0.8.0 broker implementation on top of Cloudflare Workers

TypeScript 151 2 Updated Oct 1, 2022

A full-featured Webpack + vue-loader setup with hot reload, linting, testing & css extraction.

JavaScript 9,614 4,267 Updated Mar 1, 2023
Python 2 6 Updated Mar 25, 2019

Customizable utility functions to generate vuex stores that facilitate network requests.

JavaScript 18 3 Updated Dec 9, 2022

(OLD REPO) Line-by-line profiling for Python - Current repo ->

Python 3,581 253 Updated Oct 26, 2021