Scientific Seminar: "Saddle-node bifurcation, ghost attractor and cell memory"

Speaker: Stankevich N.V., Franovich I.

Abstract. The report will discuss the results of studies [1–2], which illustrate the manifestation of cellular memory in the context of phantom attractors arising at the threshold of saddle‑node bifurcation when noise is added. The results of modeling cellular memory obtained for the EGFR model will also be discussed.
[1] Stanoev A., Nandan A. P., Koseska A. (2020). Critical level organization enables receptor networks to process time‑varying signals. Molecular systems biology, 16(2), MSB198870.
[2] Nandan A., Das A., Lott R., Koseska A. (2022). Cells use molecular working memory to navigate in changing chemoattractant fields. Elife, 11, e76825.