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Tuberculosis

Mycobacterium tuberculosis section, in a macrophage. False colours.
© Service photo / Institut Pasteur

Tuberculosis (TB) is an infectious disease caused by bacteria belonging to the Mycobacterium tuberculosis complex.

Nine million new cases of TB, and nearly two million deaths from TB, are estimated to occur around the world every year. TB is the leading cause of death among curable infectious diseases. The World Health Organization declared TB a global emergency in 1993.

Recent Updates:

March 2007: HPA TB newsletter March 2007 PDF (260 KB)

March 2007: HPA press release for World TB Day

March 2007: HPR article for World TB Day PDF (310 KB)

March 2007: Tuberculosis National Knowledge Week – National electronic Library of Infection

TB usually causes disease in the lungs (pulmonary), but can also affect other parts of the body (extra-pulmonary). Only the pulmonary form of TB disease is infectious. Transmission occurs through coughing of infectious droplets, and usually requires prolonged close contact with an infectious case. TB is curable with a combination of specific antibiotics, but treatment must be continued for at least six months.

About 8000 new cases of TB are currently reported each year in the United Kingdom. Most cases occur in major cities, particularly in London.

The Health Protection Agency aims to contribute to the elimination of TB in England through support to the National Health Service and the Department of Health in the key areas identified for controlling TB in the National Action Plan, Stopping Tuberculosis in England, published by the Chief Medical Officer in October 2004.

Through its TB Programme, the HPA co-ordinates its TB control activities, which are carried out by different parts of the organisation: the Centre for Infections, Local and Regional Services, the Regional Microbiology Network and the Centre for Emergency Preparedness and Response. The activities include local and national surveillance, laboratory diagnostic and reference services, disease control in the population, international partnership and leading edge research.


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