This continues the work from the :ref:`toy MSTIS <toy-mstis>` example. Taking the results from that, we can create a fixed bias single replica TIS simulation.
Normally you would iterate the fixed bias calculation several times in order to converge toward a flat histogram. In this particular example, we start with a well-converged result from the previous example, so we don't need to iterate.
.. notebook:: examples/toy_model_mstis/toy_mstis_5_srtis.ipynb :skip_exceptions: